Walter Scott, Jr. College of Engineering

Graduate Exam Abstract

omid masihzadeh
Ph.D. Final
Feb 19, 2010, 15:00
Engineering B103
Nonlinear laser-scanning and holographic micsrocpy
Abstract: Optical microscopy is an important tool for biomedical research. New techniques for microscopy enable new capabilities for studying biological systems. Moreover, in optical microscopy, the polarization state of the focal field strongly influences the images formed due to the impact of focal spot size, adjusting the relative strength and phase of both transverse and longitudinal field components, and manipulating interaction with the sample under study. In particular, coherent nonlinear microscopies, such as third harmonic generation (THG), and second harmonic generation, offer rich possibilities for new control over the imaging process. In this dissertation defense, I demonstrate that control over the spatial polarization state of the focal field can be used to improve the spatial resolution in a laser-scanning THG microscopy. Moreover, we show an alternative method to laser-scanning nonlinear microscopy in biological tissue, namely, nonlinear holographic microscopy.
Adviser: Randy. Bartels
Co-Adviser: N/A
Non-ECE Member: Jacob L Roberts (Physics)
Member 3: Mario C Marconi
Addional Members: N/A
Program of Study: