Biomedical Engineer Larry McIntire to Present Seminar March 7, 2003

On Friday, March 7, 2003, Colorado State University’s biomedical engineering program will host Larry McIntire, E.D. Butcher Professor and chair of the department of bioengineering at Rice University, as he presents "The Importance of Mechanical Forces in Gene Expression of Vascular Cells: Implications for Tissue Engineering." The seminar is free and open to the public and will be held in Clark A202 from 12:10 to 1 p.m. Guests are invited to attend a brief reception at noon prior to the seminar.

McIntire will be discussing the use of gene microarray analysis to study the effect of biological stimuli on gene expression profiles. The seminar will consider research using an array containing over 4000 known human genes to identify those regulated by fluid shear stress and cyclic strain exposure.

"The use of microarray technology to study the biological effects of shear stress has the potential to expedite our understanding of the role of mechanical forces in vascular biology and to allow the development of new hypotheses concerning genetic networks regulated by mechanical forces," McIntire said.

McIntire also chairs of the Institute of Biosciences and Bioengineering at Rice University. He received his bachelor and master of chemical engineering degrees from Cornell University in 1966 and his Ph.D. in chemical engineering from Princeton University in 1970. Among his honors, McIntire has received a National Institutes of Health MERIT Award and the American Institute of Chemical Engineering Food, Pharmaceutical and Bioengineering Division Award. He is a founding fellow and past president of the American Institute of Medical and Biological Engineering, past president and senior member of the Biomedical Engineering Society and past president of the North American Society of Biorheology. McIntire has been elected a Fellow of the Chemical Engineering Food, Pharmaceutical and Bioengineering Institute and the American Association for the Advancement of Science. In 2001, McIntire was elected to the National Academy of Engineering and was appointed editor-in-chief of the Annals of Biomedical Engineering effective January 2002.

His research interests include the effects of flow on mammalian-cell metabolism, molecular mechanisms of cell adhesion, tissue and cellular engineering and bioengineering aspects of vascular biology.

This seminar is the second in a series of five spring seminars sponsored by Colorado State’s biomedical engineering program. Upcoming seminars will feature Greg Stephanopoulos, MIT Bayer professor of chemical engineering and biotechnology; Clint Rubin, professor and director of the Center for Biotechnology at Stony Brook University; and Robert Nerem, Institute professor, Parker H. Petit distinguished chair of engineering in medicine, director of the Parker H. Petit Institute for Bioengineering and director of the Georgia Tech/Emory Center for the Engineering of Living Tissues.

For more information about the Colorado State University Biomedical Engineering Program seminar series, view the biomedical seminar calendar or contact Mae Lee Heble at (970) 491-1055.



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