
Contact
Office: Scott 308
Phone: 970-491-0096
Email: soham.ghosh@colostate.edu
Website: engr.colostate.edu/projects/cemlab
Dr. Soham Ghosh
Cellular Engineering and Mechanobiology Laboratory
Assistant Professor
Mechanical Engineering
School of Biomedical Engineering
Dr. Soham Ghosh is an Assistant Professor in the Department of Mechanical Engineering at Colorado State University. He is also a core faculty member of the C. Wayne McIlwraith Translational Medicine Institute, School of Biomedical Engineering, and the Program in Cell and Molecular Biology. He directs the Cellular Engineering and Mechanobiology Laboratory, located at the Translational Medicine Institute.
Dr. Ghosh’s research focuses on mechanobiology, nuclear and chromatin organization, exploring how mechanical forces regulate cellular behavior, gene expression and epigenetic modifications inside the nucleus. His work aims to uncover the fundamental mechanobiological principles that govern degenerative diseases, tissue regeneration, and cellular adaptation to mechanical stimuli. The applications of this research include understanding how different tissues age, creating regenerative medicine paradigms and countering the tissue loss in astronauts during long term space travel. Another major focus of his research group research is the study of collective cell behavior, analyzing how groups of cells coordinate their migration, adhesion, and differentiation in response to mechanical forces. This has significant implications for wound healing, fibrosis, and cancer metastasis.
Dr. Ghosh’s research has been widely published in prestigious, high-impact journals, including Nature Biomedical Engineering, Cell Reports, Biophysical Journal, Small, ACS Biomaterials Science & Engineering, Journal of the Royal Society Interface, Acta Biomaterialia, Advanced Biology, Computers in Biology and Medicine, and Frontiers in Cell and Developmental Biology.
In recognition of his research excellence, Dr. Ghosh has been awarded several external research funding as Principal Investigator (PI) from multiple federal agencies. His contributions to mechanobiology research have earned him several prestigious awards. He is a 2024 Rising Star Award recipient from the American Society of Mechanical Engineers (ASME) and a 2023 National Science Foundation CAREER Awardee. He also received the Outstanding Faculty Award from the School of Biomedical Engineering at CSU for his exceptional mentorship in research and teaching.
Beyond research, Dr. Ghosh plays leadership roles in professional organizations. He is an active member of the Biomedical Engineering Society (BMES) and ASME Bioengineering Division, frequently serving positions at the Biomedical Engineering Society Annual Meeting and the Summer Biomechanics, Bioengineering, and Biotransport Conference (SBC). He also served as reviewer for top-tier journals, including eLife, Nature Communications, Biophysical Journal, ASME Journal of Biomechanical Engineering, Tissue Engineering, Nucleus, Journal of the Royal Society Interface, and PLOS One.
As a dedicated educator, Dr. Ghosh is passionate about mentoring students and fostering scientific curiosity. He has earned multiple teaching awards for his commitment to education. In CSU he taught MECH 262: Engineering Mechanics, BIOM 200: Fundamentals of Biomedical Engineering, BIOM 441: Biomechanics and Biomaterials, and MECH/BIOM 572: Regenerative Bioengineering with Stem Cells. Many of his students have received competitive research awards, reflecting his dedication to academic mentorship.
Education
- Ph.D. 2014, Purdue University—Mechanical Engineering
- M.Tech. 2010, Indian Institute of Technology Madras—Mechanical Engineering
- B.E. 2008, Jadavpur University—Mechanical Engineering
Resources
Research Interests
- Stem Cell Engineering
- Mechanobiology
- Epigenetics