Graduate Exam Abstract
Erkang WangPh.D. Preliminary
April 14, 2021, 2:00 pm - 4:00 pm
Pump-probe microscopy of cytochrome
Abstract: Pump-probe microscopy or transient absorption microscopy can trace transient states of molecules through the transient absorption of ultrafast laser pulses. Therefore TA measured from the pump-probe microscopy offers another degree of freedom for molecular specificity. My previous work focuses on building a pump-probe microscope that can lower the photo damaging by having a fast line scanning rate, and has enhanced SNR by utilizing adaptive filter.
My next step is to utilize supercontinuum generation from photonic crystal fiber to generate tunable pump and probe wavelengths for better contrast between reduced and oxidized cytochrome.
Adviser: Jesse Wilson
Non-ECE Member: Stuart Tobet, Department of Biomedical Sciences
Member 3: Randy Bartels, Electrical and Computer Engineering
Addional Members: Diego Krapf, Electrical and Computer Engineering
Erkang Wang, Saurabh Gupta, & Jesse W Wilson (2020). Adaptive noise canceling for transient absorption microscopy. Journal of biomedical optics, 25(10), 106503. https://doi.org/10.1117/1.JBO.25.10.106503
Erkang Wang; Scott R. Domingue; Randy A. Bartels; Jesse W. Wilson, Pump-probe spectroscopy and imaging of heme proteins: temperature effects and data analysis, 09/2017, Proc. SPIE 10380, Ultrafast Nonlinear Imaging and Spectroscopy V.
Saurabh Gupta, Erkang Wang, Steven Derrien, and Jesse W. Wilson. DR-RINS: Digital real-time relative intensity noise suppressor for pump–probe spectroscopy and microscopy. Review of Scientific Instruments 92, 023704 (2021); https://doi.org/10.1063/5.0032376
Program of Study: