Group Photo Summer 2018


Back row, left to right: Yaya Fan (former MS), Ramsey Smith (CBE senior), Ning Zhao (former postdoc and current TagTeam collaboration manager), Luke Hartje (recent Ph.D. grad), Dr. Snow. Front row, left to right: Abby Ward (Chem Ph.D student), Julius Stuart (Chem Ph.D. student), Sasha Chappell (intern), Gayani Dedduwa-Mudalige (postdoc), Amanda Cherwin (REU), Holland Dierl (CBE junior), Ann Kowalski (recent Ph.D. grad).


Group Photo BIOMOD 2018


For the second year, the Snow lab has provided material support for the CSU team that has competed in the international biomolecular engineering competition BIOMOD. For more info about the project, see the [team's page]. Left to right: Ramsey Smith (CBE senior), Abby Ward (Chem Ph.D student and BIOMOD mentor), Vincent Braud, recumbant (CBE junior), Alex Frickenstein (CBE senior), Dr. Snow, Xandria Amash (CBE junior)





Principal Investigator

Christopher Snow Ph.D. [CV]
Associate Professor
Affiliations:

  • Chemical and Biological Engineering
  • Department of Biochemistry and Molecular Biology
  • Department of Chemistry
  • School of Biomedical Engineering
  • School of Advanced Materials Discovery
  • Cell and Molecular Biology Program


  • At CSU, Dr. Snow leads a research group focus on computer-guided protein and DNA engineering, particularly the engineering of crystals. Application areas of interest include bioenergy, synthetic biology, pharmacogenetics, and structural biology. Methods of particular interest include directed evolution, macromolecular crystallography, protein structure prediction, and new algorithms for reliable computational protein engineering. Dr. Christopher Snow joined the Department of Chemical and Biological Engineering in 2011, and has proceeded to join the Department of Biochemistry and Molecular Biology, the Department of Chemistry, the School of Biomedical Engineering, the Cell and Molecular Biology Program, and the School of Advanced Materials Discovery. Dr. Snow received a B.S. degree in Chemistry from MIT in 2001 and his Ph.D. in Biophysics from Stanford University in 2006. As a Howard Hughes fellow at Stanford, Dr. Snow studied the biophysics of protein folding using distributed computing. Before arriving at CSU, Dr. Snow was a Jane Coffin Childs Fellow and a KAUST Research Fellow at Caltech where he developed software for computational protein engineering, designed libraries of cellulase enzymes, and studied protein recombination using high-throughput crystallography.


    Julius Stuart

    Ph.D. Student, Chemistry (2018- )

    Julius joined the Snow Lab in January 2018 and started work characterizing porous protein crystals for applications in fluorogenic biosensing and DNA capture. He obtained a GAUSSI fellowship supporting his work to explore DNA-loaded protein crystals for barcoding applications.



    Abby Ward

    Ph.D. Student, Chemistry (2017-)

    Abby joined the Snow Lab in January 2017 and started work characterizing protein crystals with atomic force microscopy and temperature studies. Shortly after, she began working with a team of eight undergraduate students on a project using existing protein and DNA co-crystals as an exandable, designable scaffold. The project has developed to explore co-crystal crosslinking chemistry and designs of original co-crystal scaffolds. She will continue to mentor a team of undergraduate students for the BIOMOD competition for the remainder of her time at CSU. Abby recieved a B.S. degree in Chemistry Health Sciences from UCO and is currently in the Chemistry PhD Program at CSU with a specialty in Chemical Biology.


    Holland Dierl

    Undergraduate Researcher, Chemical and Biological Engineering (2018-)


    Alex Frickenstein

    Undergraduate Researcher, Chemical and Biological Engineering (2017-)


    Ramsey Smith

    Undergraduate Researcher, Chemical and Biological Engineering (2017-)


    Sergei Driga

    Undergraduate Researcher, Chemical and Biological Engineering (2018-)


    Sarah Wakumoto

    Undergraduate Researcher, Chemical and Biological Engineering (2019-)



    Group Alumni


    Gayani Dedduwa-Mudalige

    Postdoctoral Fellow (2018-2019)

    Dr. Gayani Dedduwa-Mudalige in Snow group led a protein engineering and evolution project for identification of novel protein scaffolds for intracellular imaging applications. Prior to joining Snow lab in 2018, Gayani was a postdoctoral associate in McNaughton lab at CSU, where she developed a Sortase-mediated protein evolution platform for in-cell screening. Gayani obtained her PhD from Wayne State University, Michigan. Her doctoral studies focused on studying kinetics of cisplatin interactions with bacterial ribosomal RNA and identifying platinated RNA products. Next position: mBio Diagnostics


    Ann Kowalski

    Ph.D. Student, Chemical and Biological Engineering (2012-2018)

    Ann began her PhD at CSU in August 2012 as an NSF IGERT Fellow in Bioenergy. Her work focuses on the use of protein crystals as biotemplating materials for gold nanoparticles and nanorods and other metal nanoarchitectures. She is currently developing methods to image the protein crystal scaffold through small angle x-ray scattering and atomic force microscopy. Ann received her B.S. from Clemson University in Biosystems Engineering with a focus on Environmental Engineering. Next position: IM Flash


    Thaddaus Huber

    Ph.D. Student, Chemical and Biological Engineering (2011-2017)
    Current position: WRF Innovation Fellow in Protein Design, Postdoctoral Fellow in the Neil King lab at UW


    Amanda Cherwin

    Summer Undergraduate Researcher (2018)
    Current position: Finishing a Biomolecular Engineering degree at the Milwaukee School of Engineering.


    William Wright

    Undergraduate Researcher, Chemical and Biological Engineering (2017)


    Eli McPherson

    Undergraduate Researcher, Chemical and Biological Engineering (2014-2017)


    Samantha Sloan

    Undergraduate Researcher, Chemical and Biological Engineering (2015-2017)
    Current position: Emerson Automation Solutions.


    Stacey Zintgraff

    Undergraduate Researcher, Chemical and Biological Engineering (2015-2017)
    Current position: Aspen Beverage Group.


    Jeffrey Bennett

    Undergraduate Researcher, Chemical and Biological Engineering (2015-2016)
    Current position: Ph.D. student in the Abolhasani lab at North Carolina State University.


    David Andales

    Undergraduate Researcher, Chemical and Biological Engineering (2014-2018)
    Current Position: Niagara Bottling.


    Carolyn Keating

    Undergraduate Researcher, Chemical and Biological Engineering (2013-2018)


    Karina Appel

    Undergraduate Researcher in the Lab (2012-2016), Chemical and Biological Engineering
    Current position: Development Associate at Bayer Pharmaceuticals


    Luke Hartje

    Ph.D. Student (2014-2018), Biochemistry and Molecular Biology
    Current position: Researcher at ArcherDX


    Lucas Johnson

    Ph.D. Student (2011-2016), Chemical and Biological Engineering
    Current position: Researcher at OptiEnz


    Mark Lunt

    Masters Student, Chemical and Biological Engineering
    Current position: Senior Software Developer for General Dynamics Information Technology.


    Jarad Yost

    Undergraduate Student, Chemical and Biological Engineering (2013-2015)
    Current position: Masters student at Texas A&M University.


    Jacob Sebesta

    Masters Student (2013-2015), Chemical and Biological Engineering
    Current position: Ph.D. student in the laboratory of Christie Peebles.


    Matt Baker

    Graduate Student, Biomedical Engineering (2011-2012)
    Current position: KBI Biopharma.


    Joseph Chiavetta

    Undergraduate, Chemical and Biological Engineering (2012-2013)