Publications

• Kowalski, Ann; Johnson, Lucas; Dierl, Holland; Park, Sehoo; Huber, Thaddaus; Snow, Chris. "Porous protein crystals as scaffolds for enzyme immobilization" Biomaterials Science, vol. 7, no.5, 2019, pp. 1898-1904.
• "Porous crystals as scaffolds for structural biology." Current opinion in structural biology, December, 2019.
• Sun, Guotao; Tang, Jianguo; Snow, Chris; Li, Zhenhua; Zhang, Yu; Wang, Yao; Belfiore, Laurence. "Drug Sensing Protein Crystals Doped with Luminescent Lanthanide Complexes" Crystal Growth & Design, vol. 19, no.10, 2019, pp. 5658-5664.
• Rossmassler, Karen; Snow, Chris; Taggart, Dora; Brown, Casey; De Long, Susan. "Advancing biomarkers for anaerobic o-xylene biodegradation via metagenomic analysis of a methanogenic consortium" Applied Microbiology and Biotechnology, vol. 103, no.10, 2019, pp. 4177-4192.
• Zhang, Yu; Zhang, Xiaoting; Tang, Jianguo; Snow, Chris; Sun, Guotao; Kowalski, Ann; Hartje, Luke; Zhao, Ning; Wang, Yao; Belfiore, Laurence. "Synthesis of Luminescent Lanthanide Complexes within Crosslinked Protein Crystal Matrices" CrystEngComm, vol. 20, 2018, pp. 2267-2277.
• Hartje, Luke; Snow, Christopher. "Protein crystal based materials for nanoscale applications in medicine and biotechnology" WIREs Nanomedicine and Nanobiotechnology, vol. 11, no.4, 2018, pp. e1547.
• Wang, Die; Shen, Wenfei; Tang, Jianguo; Wang, Yao; Liu, Jixian; Wang, Xinzhi; Yang, Renqiang; Snow, Chris; Huang, Linjun; Jiao, Jiqing; Wang, Yanxin; Wang, Wei; Belfiore, Laurence. "Enhancing the Power Conversion Efficiency for Polymer Solar Cells by Incorporating Luminescent Nanosolid Micelles as Light Converter" ACS Applied Energy Materials, vol. 1, no.4, 2018, pp. 1445-1454.
• Kowalski, Ann; Nemeth, Richard; Zintgraff, Stacey; Sloan, Samantha; Huber, Thaddaus; Ciesielski, Peter; Ackerson, Chris; Snow, Chris. "Protein Crystals as Molds for Seeded Gold Nanorod Growth" ACS Nano, .
• Hartje, Luke; Bui, Hieu; Andales, David; James, Susan; Huber, Thaddaus; Snow, Chris. "Characterizing the Cytocompatibility of Various Cross-Linking Chemistries for the Production of Biostable Large-Pore Protein Crystal Materials" ACS Biomaterials Science \& Engineering, 0, January (1st Quarter/Winter), 2018, pp. null.
• Huber, Thaddaus; McPherson, E; Keating, C; Snow, Chris. "Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals." Bioconjugate chemistry, vol. 29, no.1, 2017, pp. 17-22.
• Hartje, Luke; Munsky, Brian; Ni, Thomas; Ackerson, Chris; Snow, Chris. "Adsorption-Coupled Diffusion of Gold Nanoclusters within a Large-Pore Protein Crystal Scaffold." The journal of physical chemistry. B, vol. 121, no.32, 2017, pp. 7652-7659.
• Hartje, Luke; Munsky, Brian; Ni, Thomas; Ackerson, Chris; Snow, Chris. "Adsorption-Coupled Diffusion of Gold Nanoclusters within a Large-Pore Protein Crystal Scaffold." The journal of physical chemistry. B, vol. 121, no.32, 2017, pp. 7652-7659.
• Lunt, Mark; Snow, Chris. "A Structure-Based Design Protocol for Optimizing Combinatorial Protein Libraries" Methods in Molecular Biology (Clifton, N.J.), vol. 1414, 2016, pp. 99–138.
• Huber, Thaddaus; Hartje, Luke; McPherson, Eli; Kowalski, Ann; Snow, Chris. "Programmed Assembly of Host–Guest Protein Crystals" Small, December, 2016, pp. n/a–n/a.
• Johnson, Lucas; Park, Sehoo; Gintner, Lucas; Snow, Chris. "Characterization of supercharged cellulase activity and stability in ionic liquids" Journal of Molecular Catalysis B: Enzymatic, vol. 132, October (4th Quarter/Autumn), 2016, pp. 84–90.
• Reynolds, Evan; McHenry, Matthew; Cannac, Fabien; Gober, Joshua; Snow, Chris; Brustad, Eric. "An Evolved Orthogonal Enzyme/Cofactor Pair" Journal of the American Chemical Society, vol. 138, no.38, 2016, pp. 12451–12458.
• Bennett, Jeffrey; Snow, Chris. "Optimizing Shape Complementarity Scoring Parameters for Recognition of Authentic Protein Crystal Packing Arrangements" Crystal Growth & Design, vol. 16, no.9, 2016, pp. 5579–5583.
• Johnson, Lucas; Snow, Chris. "Molecular dynamics simulations of cellulase homologs in aqueous 1-ethyl-3-methylimidazolium chloride" Journal of Biomolecular Structure & Dynamics, July (3rd Quarter/Summer), 2016, pp. 1–13.
• Kowalski, Ann; Huber, Thaddaus; Ni, Thomas; Hartje, Luke; Appel, K; Yost, J; Ackerson, Chris; Snow, Chris. "Gold nanoparticle capture within protein crystal scaffolds." Nanoscale, vol. 8, no.25, 2016, pp. 12693-6.
• Meyers, J.; Gray, Meg; Kuklinski, W.; Beck-Johnson, Lindsay; Snow, Chris; Black IV, William; Partin, K.; Foy, Brian. "Characterization of the target of ivermectic, the glutamate-gated chloride channel, from Anopheles gambiae" Journal of Ex. Biology, 2015.
• Havird, Justin; Whitehill, Nicholas; Snow, Chris; Sloan, Dan. "Conservative and compensatory evolution in oxidative phosphorylation complexes of angiosperms with highly divergent rates of mitochondrial genome evolution" Evolution, vol. 69, no.12, 2015, pp. 3069–3081.
• Johnson, L; Gintner, L; Park, S; Snow, Chris. "Discriminating between stabilizing and destabilizing protein design mutations via recombination and simulation." Protein engineering, design & selection : PEDS, vol. 28, no.8, 2015, pp. 259-67.
• Foy, Brian; Gray, Meg; Kuklinski, Wojtek; Johnson, Lucas; Snow, Chris; Black IV, William; Partin, Kathryn; Foy, Brian. "Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae" The Journal of Experimental Biology, vol. 218, May, 2015, pp. 1478-86.
• Meyers, J; Gray, Michael; Kuklinski, W; Johnson, L; Snow, Chris; Black, 4th, W; Partin, K; Foy, Brian. "Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae." The Journal of experimental biology, vol. 218, Pt 10, 2015, pp. 1478-86.
• Johnson, Lucas; Huber, Thaddaus; Snow, Chris. "Methods for library-scale computational protein design" Methods in Molecular Biology (Clifton, N.J.), vol. 1216, 2014, pp. 129–159.
• Brinkmann-Chen, Sabine; Flock, Tilman; Cahn, Jackson; Snow, Chris; Brustad, Eric; McIntosh, John; Meinhold, Peter; Zhang, Liang; Arnold, Frances. "General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH" Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no.27, 2013, pp. 10946–10951.
• Chen, Mike M. Y., ; Snow, Chris; Vizcarra, Christina; Mayo, Stephen; Arnold, Frances. "Comparison of random mutagenesis and semi-rational designed libraries for improved cytochrome P450 BM3-catalyzed hydroxylation of small alkanes" PROTEIN ENGINEERING DESIGN & SELECTION, vol. 25, no.4, 2012, pp. 171-178.
• Smith, Margie; Rentmeister, A; Snow, Chris; Wu, T; Farrow, M; Mingardon, F; Arnold, F. "A diverse set of family 48 bacterial glycoside hydrolase cellulases created by structure-guided recombination." The FEBS journal, vol. 279, no.24, 2012, pp. 4453-65.
• Liu, Xiang; Bastian, Sabine; Snow, Chris; Brustad, Eric; Saleski, Tatyana; Xu, Jian-He; Meinhold, Peter; Arnold, Frances. "Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol" Journal of biotechnology, September, 2012.
• Brustad, E; Lelyveld, V; Snow, Chris; Crook, N; Jung, S; Martinez, F; Scholl, T; Jasanoff, A; Arnold, F. "Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin." Journal of molecular biology, vol. 422, no.2, 2012, pp. 245-62.
• Rentmeister, Andrea; Brown, Tristan; Snow, Chris; Carbone, Martina; Arnold, Frances. "Engineered Bacterial Mimics of Human Drug Metabolizing Enzyme CYP2C9" ChemCatChem, vol. 3, no.6, 2011, pp. 1065-1071.
• Bastian, Sabine; Liu, Xiang; Meyerowitz, Joseph; Snow, Chris; Chen, Mike; Arnold, Frances. "Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli" Metabolic Engineering, vol. 13, no.3, 2011, pp. 345–352.
• Ng, Albert; Snow, Chris. "Polarizable protein packing" Journal of Computational Chemistry, vol. 32, no.7, 2011, pp. 1334–1344.
• Lewis, Jared; Mantovani, Simone; Fu, Yu; Snow, Chris; Komor, Russell; Wong, Chi-Huey; Arnold, Frances. "Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates" Chembiochem: A European Journal of Chemical Biology, vol. 11, no.18, 2010, pp. 2502–2505.
• Lucent, Del; Snow, Chris; Aitken, Colin; Pande, Vijay. "Non-bulk-like solvent behavior in the ribosome exit tunnel" PLoS Computational Biology, vol. 6, no.10, 2010, pp. e1000963.
• Heinzelman, P; Komor, R; Kanaan, A; Romero, P; Yu, X; Mohler, S; Snow, Chris; Arnold, F. "Efficient screening of fungal cellobiohydrolase class I enzymes for thermostabilizing sequence blocks by SCHEMA structure-guided recombination." Protein engineering, design & selection : PEDS, vol. 23, no.11, 2010, pp. 871-80.
• Heinzelman, Pete; Snow, Chris; Smith, Matthew; Yu, Xinlin; Kannan, Arvind; Boulware, Kevin; Villalobos, Alan; Govindarajan, Sridhar; Minshull, Jeremy; Arnold, Frances. "SCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stability" The Journal of Biological Chemistry, vol. 284, no.39, 2009, pp. 26229–26233.
• Heinzelman, Pete; Snow, Chris; Wu, Indira; Nguyen, Catherine; Villalobos, Alan; Govindarajan, Sridhar; Minshull, Jeremy; Arnold, Frances. "A family of thermostable fungal cellulases created by structure-guided recombination" Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no.14, 2009, pp. 5610–5615.
• Loksha, Ilya; Maiolo, 3rd, James R; Hong, Cheng; Ng, Albert; Snow, Chris. "SHARPEN-systematic hierarchical algorithms for rotamers and proteins on an extended network" Journal of Computational Chemistry, vol. 30, no.6, 2009, pp. 999–1005.
• Fasan, Rudi; Meharenna, Yergalem; Snow, Chris; Poulos, Thomas; Arnold, Frances. "Evolutionary history of a specialized p450 propane monooxygenase" Journal of Molecular Biology, vol. 383, no.5, 2008, pp. 1069–1080.
• Petrone, Paula; Snow, Chris; Lucent, Del; Pande, Vijay. "Side-chain recognition and gating in the ribosome exit tunnel" Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no.43, 2008, pp. 16549–16554.
• "Hunting for predictive computational drug-discovery models" Expert Review of Anti-Infective Therapy, vol. 6, no.3, 2008, pp. 291–293.
• Ben-Hur, Asa; Draper, Bruce; Anderson, Chuck; Snow, Chris; others, . "Large margin methods for partner specific prediction of interfaces in protein complexes" Colorado State University. Libraries, 2007.
• Li, Yougen; Drummond, D; Sawayama, Andrew; Snow, Chris; Bloom, Jesse; Arnold, Frances. "A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments" Nature Biotechnology, vol. 25, no.9, 2007, pp. 1051–1056.
• Suydam, Ian; Snow, Chris; Pande, Vijay; Boxer, Steven. "Electric fields at the active site of an enzyme: direct comparison of experiment with theory" Science (New York, N.Y.), vol. 313, no.5784, 2006, pp. 200–204.
• Snow, Chris; Rhee, Young; Pande, Vijay. "Kinetic definition of protein folding transition state ensembles and reaction coordinates" Biophysical Journal, vol. 91, no.1, 2006, pp. 14–24.
• Snow, Chris; Sorin, Eric; Rhee, Young; Pande, Vijay. "How well can simulation predict protein folding kinetics and thermodynamics?" Annual Review of Biophysics and Biomolecular Structure, vol. 34, 2005, pp. 43–69.
• Fujitani, Hideaki; Tanida, Yoshiaki; Ito, Masakatsu; Jayachandran, Guha; Snow, Chris; Shirts, Michael; Sorin, Eric; Pande, Vijay. "Direct calculation of the binding free energies of FKBP ligands" The Journal of Chemical Physics, vol. 123, no.8, 2005, pp. 084108.
• Chong, Lillian; Snow, Chris; Rhee, Young; Pande, Vijay. "Dimerization of the p53 oligomerization domain: identification of a folding nucleus by molecular dynamics simulations" Journal of Molecular Biology, vol. 345, no.4, 2005, pp. 869–878.
• Singhal, Nina; Snow, Chris; Pande, Vijay. "Using path sampling to build better Markovian state models: predicting the folding rate and mechanism of a tryptophan zipper beta hairpin" The Journal of Chemical Physics, vol. 121, no.1, 2004, pp. 415–425.
• Snow, Chris; Qiu, Linlin; Du, Deguo; Gai, Feng; Hagen, Stephen; Pande, Vijay. "Trp zipper folding kinetics by molecular dynamics and temperature-jump spectroscopy" Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no.12, 2004, pp. 4077–4082.
• Luisi, Donna; Snow, Chris; Lin, Jo-Jin; Hendsch, Zachary; Tidor, Bruce; Raleigh, Daniel. "Surface salt bridges, double-mutant cycles, and protein stability: an experimental and computational analysis of the interaction of the Asp 23 side chain with the N-terminus of the N-terminal domain of the ribosomal protein l9" Biochemistry, vol. 42, no.23, 2003, pp. 7050–7060.
• Pande, Vijay; Baker, Ian; Chapman, Jarrod; Elmer, Sidney; Khaliq, Siraj; Larson, Stefan; Rhee, Young; Shirts, Michael; Snow, Chris; Sorin, Eric; Zagrovic, Bojan. "Atomistic protein folding simulations on the submillisecond time scale using worldwide distributed computing" Biopolymers, vol. 68, no.1, 2003, pp. 91–109.
• Snow, Chris; Zagrovic, Bojan; Pande, Vijay. "The Trp cage: folding kinetics and unfolded state topology via molecular dynamics simulations" Journal of the American Chemical Society, vol. 124, no.49, 2002, pp. 14548–14549.
• Snow, Chris; Nguyen, Houbi; Pande, Vijay; Gruebele, Martin. "Absolute comparison of simulated and experimental protein-folding dynamics" Nature, vol. 420, no.6911, 2002, pp. 102–106.
• Zagrovic, Bojan; Snow, Chris; Shirts, Michael; Pande, Vijay. "Simulation of folding of a small alpha-helical protein in atomistic detail using worldwide-distributed computing" Journal of Molecular Biology, vol. 323, no.5, 2002, pp. 927–937.
• Zagrovic, Bojan; Snow, Chris; Khaliq, Siraj; Shirts, Michael; Pande, Vijay. "Native-like mean structure in the unfolded ensemble of small proteins" Journal of Molecular Biology, vol. 323, no.1, 2002, pp. 153–164.