Our lab focuses on the architecture of mammalian cells. The main expertise of the team is in single-molecule biophysics experiments at the nanometer scale. We place particular emphasis on the actin-based cytoskeleton and its role in the dynamic organization of the plasma membrane.

Research Projects


  • May 2021 – New article in FASEB J
    Our article, in collaboration with the Buffone Lab, about Cdc42 localization role in mouse sperm, was accepted in the FASEB Journal.
  • March 2021 – New article in NJP
    Our article about identifying diffusive states in live cells using a hidden Markov model was accepted for publication in New Journal of Physics.
  • March 2021 – New NIH award
    In collaboration with the Teves lab at Virginia Commonwealth University, we have received the R03 grant “Trafficking of proteins: relevance to male fertility”.
  • January 2021 – New article in JCIS
    Congratulations to Hasan! Our article “Dynamics of long-term protein aggregation on low-fouling surfaces” was accepted for publication in the Journal of Colloid & Interface Science.
  • December 2020 – New article in NJP
    Congratulations to Samu Thapa! Our article on the large deviations test for Brownian motion was accepted for publication in New Journal of Physics.
  • July 2020 – Congratulations to Terrance
    Terrance Bishop has submitted his MS thesis to the graduate school.
  • June 2020 – New article in PRL
    Our article about heterogeneous diffusion in the cytoplasm, in collaboration with Matthias Weiss, was accepted for publication in Phys. Rev. Lett.
  • May 2020 – Promotion to Full Professor
    Diego was promoted to the rank of full professor in the Department of Electrical and Computer Engineering at CSU
  • March 2020 – Welcome to Takuma Akimoto
    Takuma Akimoto is visiting our lab from Tokyo University of Science
  • March 2020 – Welcome to Erez Aghion
    Erez is visiting our lab from the Max Planck Institute for the Physics of Complex Systems
  • January 2020 –  6th CSMMM
    The 6th Colorado Single Molecules in Membranes Meeting is taking place at CU Denver on January 10.
  • November 2019 –  Article in Acta Biomaterialia
    Congratulations to Hasan! Our article on surface characterization techniques has been accepted for publication.
  • August 2019 –  Article in Physics Today
    Our article has been accepted for publication in Physics Today and is appearing in the September issue.
  • August 2019 –  Welcome to Dominic
    Dominic Asebiah, a graduate student in materials science is starting a 10-week rotation in our lab.
  • July 2019 –  Congratulations to Eric!
    Eric has successfully defended his Ph.D. thesis.
  • May 2019 –  New article in Scientific Reports
    Our article on mu-opioid receptors in collaboration with the Hentges lab has been accepted to Scientific Reports
  • January 2019 –  César Milstein Award
    Diego Krapf received a Milstein award to spend four months in the IBR (Rosario) and the IBYME (Buenos Aires) in Argentina.
  • December 2018 –  New article in PRX
    Our article on the power spectra of individual fractional Brownian motion trajectories was accepted in Physical Review X.
  • December 2018 – New article in PRE
    Our article on the identification of the diffusive type of motion in the plasma membrane using ARFIMA models was accepted for publication.
  • November 2018 – George T. Abell Outstanding Mid-Career Faculty Award

    Diego Krapf received the Outstanding Mid-Career Faculty Award from the Walter Scott, Jr. College of Engineering at CSU.


PI: Diego Krapf
Electrical and Computer Engineering and School of Biomedical Engineering
Colorado State University

Phone: (970) 491-4255
E-mail: diego.krapf@colostate.edu

Our labs are located in the third floor of the Scott Bioengineering Building.