Our lab focuses on the architecture of mammalian cells. The main expertise of the team is in single-molecule biophysics experiments at the nanometer scale. We place particular emphasis on the actin-based cytoskeleton and its role in the dynamic organization of the plasma membrane.

Research Projects


  • November 2019 –  Article in Acta Biomaterialia
    Congratulations to Hasan! Our article on surface characterization techniques has been accepted for publication.
  • August 2019 –  Article in Physics Today
    Our article has been accepted for publication in Physics Today and is appearing in the September issue.
  • August 2019 –  Welcome to Dominic
    Dominic Asebiah, a graduate student in materials science is starting a 10-week rotation in our lab.
  • July 2019 –  Congratulations to Eric!
    Eric has successfully defended his PhD thesis.
  • May 2019 –  New article in Scientific Reports
    Our article on mu-opioid receptors in collaboration with the Hentges lab has been accepted to Scientific Reports
  • January 2019 –  César Milstein Award
    Diego Krapf received a Milstein award to spend four months in the IBR (Rosario) and the IBYME (Buenos Aires) in Argentina.
  • December 2018 –  New article in PRX
    Our article on the power spectra of individual fractional Brownian motion trajectories was accepted in Physical Review X.
  • December 2018 – New article in PRE
    Our article on the identification of the diffusive type of motion in the plasma membrane using ARFIMA models was accepted for publication.
  • November 2018 – George T. Abell Outstanding Mid-Career Faculty Award

    Diego Krapf received the Outstanding Mid-Career Faculty Award from the Walter Scott, Jr. College of Engineering at CSU.

  • September 2018 – Congratulations to Bryce!

    Bryce Schroder successfully defended his PhD thesis.

  • September 2018 – New article in JCS

    Our article on actin dynamics during the acrosome reaction in mouse sperm, in collaboration with the Buffone lab, was accepted to the Journal of Cell Science.

  • September 2018 – Welcome to Guillermina Luque from the IBYME in Buenos Aires

    Guillermina is spending one month in our lab.

  • August 2018 – New article in ACS Appl. Mater. Interfaces

    Congratulations to Hasan! Our article on surfaces that mimic the vascular glycocalyx was accepted for publication.

  • July 2018 – New article in JCP

    Our article with Denis Grebenkov on the diffusion of molecules in thin extracellular spaces was accepted for publication in the Journal of Chemical Physics.

  • July 2018 – New article in Comput. Stat. Data Anal.

    Our article on the recurrence method for change point detection was accepted for publication in Computational Statistics and Data Analysis.

  • May 2018 – New article in JCS

    Congratulations to Xinran and Maria Gracia! Our manuscript on the actin structure in the mouse sperm flagellum was accepted for publication in Journal of Cell Science.

  • April 2018 – New article in JBC

    Our manuscript about the function of PKA localization in sperm during capacitation, in collaboration with Darío Krapf at UNR, was accepted for publication in the Journal of Biological Chemistry.

  • April 2018 – Interdisciplinary Scholarship Award

    Diego Krapf received the Interdisciplinary Scholarship Award from the Office of the Vice President for Research at CSU.

    • April 2018 – Congratulations to Patrick!

      Patrick Mannion received the SBME Undergraduate Award for Outstanding Research.

PI: Diego Krapf
Associate Professor
Electrical and Computer Engineering and School of Biomedical Engineering
Colorado State University

Phone: (970) 491-4255
E-mail: diego.krapf@colostate.edu

Our labs are located in the third floor of the Scott Bioengineering Building.