Krapf Research Lab

 

 
Welcome to the Krapf Research Lab!
Our work focuses on single-molecule biophysics experiments at the nanometer scale. The nature of this field is highly interdisciplinary, crossing the boundaries of Engineering, Physics and Biology.
The techniques we use in our research consist of imaging tools for single-molecule detection and tracking, and nanomanipulation instruments like optical tweezers. We aim at studying membrane dynamics and protein-DNA interactions both in vitro and in live mammalian cells and developing optical platforms for low-cost high-sensitive sensors to diagnose infectious diseases.
If you are interesting in working with our group, please do not hesitate to contact us.


Group
Diego Krapf, Ty Wojcik, Aubrey Weigel, Kristen Jevsevar, Blair Simon and Nathan Proper in Cameron Pass.

PI: Dr. Diego Krapf
Assistant Professor
Electrical and Computer Engineering and School of Biomedical Engineering
Colorado State University
1320 Campus Delivery
Fort Collins, CO 80523-1320

Tel. (970) 491-4255
e-mail: krapf@engr.colostate.edu

Labs: ERC A102 and A108


News

February 2011.

Aubrey's paper on ergodicity breaking in the membrane of HEK cells published in PNAS.

April 2010.

NSF

Our NSF proposal Membrane Dynamics Underlying Kv2.1 Cluster Formation has been awarded.

 

April 2010. We finished remodeling our wet lab.

Here are some pictures of the original A102 space, the work and the finished lab.

March 2010.

SNOWSHOEING 2010

This year we went to Cameron Pass in the Poudre Canyon. Great fun. Here are some pictures.

In the news

"TB or not TB?" Our work on tuberculosis highlighted in an article in Scientific American.
"Revolutionizing How We Detect Tuberculosis" Change.org posted an article on our work.
Listen here to the broadcast on our work in Colorado Public Radio.

Senior design projects

Our TB detection senior design project won two sponsorships: one from Agilent and one from IEEE Centennial Subsection.
Nathan won an award to travel to the APS March Meeting in Portland and present his work.


January 2010.

The Massachusetts Society for Medical Research posted a great breakthrough story focusing on our work in TB detection. The article can be found at http://www.whatayear.org/01_10.html .

December 2009.

In the news

CSU featured an article on our TB detection project.


Our lab

We have completed remodeling the lab at A108, and it looks great!


November 2009
.

Biophysical Society Meeting

Aubrey's work on Kv2.1 channels was selected for a talk at the Biophysical Society Annual Meeting.

Colorado Photonics Association Meeting

Nathan and Jeremy were again awarded a prize for the best poster of the meeting! This time at the CPIA annual meeting in Boulder, CO.

October 2009.

APS 4 Corners Meeting

Nathan and Jeremy were awarded a prize for the best undergraduate poster of the meeting in Golden, CO. They presented their work in field-friendly infectious disease biosensors.

OSA Spotlight

Our research in the development of TB biosensors was recognized by OSA as a spotlight of the Optical Society's Annual Meeting, Frontiers in Optics. Scientists Take Step Toward Simple and Portable Tuberculosis Tests for Developing World.

April 2009. CSU day at the State Capitol

We represented the School of Biomedical Engineering at the State Capitol on April 17. We discussed our research efforts and the work the program is doing with Colarado Senators and Representatives and with members of the University Board. Governor Bill Ritter made a surprise visit to the CSU exhibit and he took time to talk with us about our program. Here are some pictures of the event and a letter from the Governor.

Group
Diego Krapf, Barb Smith and Aubrey Weigel posing for a shot with Governor Ritter (second from left) after showing him the work the program is doing in tuberculosis detection and joint prosthetics.