Our labs develop materials for biomedical applications with structural, chemical, and topographical cues, by tuning their composition, macromolecular assembly, nanoscale structure, and microscale structure. Materials of interest include nanoscale polyelectrolyte multilayer coatings of bioactive molecules, porous three-dimensional nanofiber tissue scaffolds, polyelectrolyte complex nanoparticles, and nanostructured metal oxide coatings.
SuMR research fellows will learn techniques used to fabricate and qualify nanobimoaterials, including advanced spectroscopic and microscopic techniques. SuMR fellows also have the opportunity to study the responses of blood, bacteria, and mammalian cells to surfaces designed to modulate immune responses, blood clotting, and stem cell differentiation. Current interests include evaluating cellular inflammation and osteogenic differentiation of human mesenchymal stem cells. This opportunity welcomes applications from students interested in materials science, biomaterials engineering, tissue engineering, and cell-material interactions.
Contact: For additional information and to apply, please contact Prof. Matt Kipper (matthew.kipper@colostate.edu) and Prof. Ketul Popat (Ketul.Popat@colostate.edu).
References:
R.M. Sabino, M.J. Kipper, A.F. Martins, K.C. Popat, “Improved in vitro endothelialization on nanostructured titania with tannin/glycosaminoglycan-based polyelectrolyte multilayers,” In vitro models (2022). DOI: 10.1007/s44164-022-00024-x
L.Y.C. Madruga, K.C. Popat, R.C. Balaban, and M.J. Kipper, “Enhanced blood coagulation and antibacterial activities of carboxymethyl-kappa-carrageenan-containing nanofibers.” Carbohydrate Polymers (2021) 273:118541. DOI: 10.1016/j.carbpol.2021.118541
T. Wigmosta, K.C. Popat, and M.J. Kipper, “Gentamicin-Releasing Titania Nanotube Surfaces Inhibit Bacteria and Support Adipose-Derived Stem Cell Growth in Cocultures,” ACS Applied Bio Materials (2021) 4(6): 4936-4945. DOI:10.1021/acsabm.1c00225.