Dr. Bark works at the interface of engineering, hematology, and vascular surgery with a focus on the interactions of blood and medical devices. He is the Chair of the Biorheology Scientific Standardization Committee of the International Society of Thrombosis and Haemostasis (ISTH), with goals of bringing fluids to the ISTH community in a digestible form.

The overarching goal of his lab is to identify how mechanical stress impacts upon cell and protein function in the cardiovascular system, while advancing tools to diagnose and treat disease. They specifically focus on the effects on blood from mechanical circulatory support, artificial heart valves, and other blood contacting medical devices.