Graduate Exam Abstract

Patrick Stockton

Ph.D. Preliminary
May 22, 2020, 12:00 pm - 2:00 pm
Single Pixel Microscopy: Computational imaging with Spatial Frequency Projection Temporal Encoding

Abstract: Imaging with spatial frequency projections allows for a surprisingly versatile encoding mechanism for computational imaging. This strategy allows a single microscope to operate in many different regimes with minor changes to the base microscope configuration. Using a simple spinning disc and coherent illumination, I demonstrate that 1D microscope line images can be extend to the 2D plane with holographic-like reconstruction of scattered spatially coherent light or spatially incoherent-light (through incoherent inelastic scattering or fluorescent emission) detected light power. I obtain quantitative phase information from an object by modifying the collection geometry with a spatial filter in the detection arm. I also generalize the line imaging methods three-dimensional (3D) tomography. In addition, applying the spatial frequency coded illumination configuration and an ultrafast, pulsed laser source, enables super-resolution imaging. Finally, hyperspectral information can be realized using the same encoding strategy applied to the spectral domain instead of the spatial domain.

Adviser: Randy Bartels
Co-Adviser: NA
Non-ECE Member: Jennifer Mueller, Mathematics
Member 3: Ali Pezeshki, Electrical Engineering
Addional Members: Jesse Wilson, Electrical Engineering

1) Patrick A. Stockton, Jeffery J. Field, Randy A. Bartels, "Single pixel quantitative phase imaging with spatial frequency projections" Methods 136, 24-34 (2018),
2) Patrick A. Stockton, Keith A Wernsing, Jeffery J. Field, Jeff Squier, Randy A. Bartels, "Fourier computed tomographic imaging of two dimensional fluorescent objects", APL Photonics 4, (2019),
3) Patrick. A. Stockton, M. Torabzadeh, B. J. Tromberg, and R. A. Bartels, "Fast Hyperspectral Detection of the Frequency Response of Highly Scattering Tissue using a Femtosecond Pulse with Light Labeling," in Frontiers in Optics / Laser Science, OSA Technical Digest (Optical Society of America, 2018),
4) Sandro Heuke, Siddharth Sivankutty, Camille Scotte, Patrick Stockton, Randy A. Bartels, Anne Sentenac, and Hervé Rigneault, "Spatial frequency modulated imaging in coherent anti-Stokes Raman microscopy," Optica 7, 417-424 (2020),
5) R. A. Bartels, K. A. Wernsing, P. Stockton, J. J. Field and J. Squier, "Spatial frequency projection super resolution imaging," 2018 Conference on Lasers and Electro-Optics (CLEO), San Jose, CA, 2018, pp. 1-2.
6) Camille Scotté, Siddharth Sivankutty, Patrick Stockton, Randy A. Bartels, and Hervé Rigneault, "Compressive Raman imaging with spatial frequency modulated illumination," Opt. Lett. 44, 1936-1939 (2019),
7) Robert J. Stokoe, Patrick A. Stockton, Ali Pezeshki, Randy A. Bartels, "Theory and applications of structured light single pixel imaging," Proc. SPIE 10499, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXV, 104990E (23 February 2018),
8) Mohammad Torabzadeh, Patrick Stockton, Gordon T. Kennedy, Rolf B. Saager, Anthony J. Durkin, Randy A. Bartels, Bruce J. Tromberg, "hyperspectral characterization of tissue simulating phantoms using a supercontinuum laser in a spatial frequency domain imaging instrument," Proc. SPIE 10486,
9) Reed Hollinger, Clayton Bargsten, Vyacheslav N. Shlyaptsev, Vural Kaymak, Alexander Pukhov, Maria Gabriela Capeluto, Shoujun Wang, Alex Rockwood, Yong Wang, Amanda Townsend, Amy Prieto, Patrick Stockton, Alden Curtis, and Jorge J. Rocca, "Efficient picosecond x-ray pulse generation from plasmas in the radiation dominated regime," Optica 4, 1344-1349 (2017)

Program of Study: