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Graduate Exam Abstract


Tucker Kern

M.S. Final

May 13, 2014, 11:00 AM

Scott Bioengineering Odyssey Design Studio

Design of Integrated On-chip Impedance Sensors


Abstract: In this thesis two integrated sensor systems for measuring the impedance of a device under test (DUT) are presented. Both sensors have potential applications in label-free affinity biosensors for biological and bio-medical analysis. The first sensor is a purely capacitive sensor that operates on the theory of capacitive division. Test capacitance is placed within a capacitive divider and produces an output voltage proportional to its value. This voltage is then converted to a time- domain signal for easy readout. The prototype capacitive sensor shows a resolution of 5 fF on a base of 500 fF, which corresponds to a 1 % resolution. The second sensor, a general purpose impedance sensor calculates the ratio between a DUT and reference impedance when stimulated by a sinusoidal signal. Computation of DUT magnitude and phase is accomplished in silicon via mixed-signal division and a phase module. An automatic gain controller (AGC) allows the sensor to measure impedance from 30 Ω to 2.5 MΩ with no more than 10 % error and a resolution of at least .44 %. Prototypes of both sensing topologies were implemented in a .18 μm CMOS process and their operation in silicon was verified. The prototype capacitive sensor required a circuit area of .014 mm2 and successfully demonstrated a resolution of 5 fF in silicon. A prototype impedance sensor without the phase module or AGC was implemented with a circuit area of .17 mm2 . Functional verification of the peak capture systems and mixed-signal divider was accomplished. The complete implementation of the impedance sensor, with phase module and AGC, requires an estimated .28 mm2 of circuit area.

Adviser: Tom Chen
Co-Adviser: N/A
Non-ECE Member: Stuart Tobet
Member 3: Ali Pezeshki
Addional Members: N/A

Publications:
Kern, T.; Chen, T., "A 0.18 μm integrated impedance sensor using a novel mixed-signal divider and automatic gain control," Circuits and Systems (ISCAS), 2014 IEEE International Symposium on, (in press)
Kern, T.; Chen, T., "A low-power, offset-corrected potentiostat for chemical imaging applications," Circuits and Systems (LASCAS), 2013 IEEE Fourth Latin American Symposium on,


Program of Study:
ECE534
ECE571
ECE513
ECE536
ECE580A4
ECE658
ECE699
N/A